| Gene name: | MIR30D |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | OVCAR-5,OWA42,MDA-MB-231,T47D,HCT116 |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | We found that mir-30d inhibitor transfection led to a significant cell-cycle arrest at the G0/G1 phase.Finally, we observed that transfection of a mir-30d inhibitor not only significantly blocked cancer cell proliferation but also remarkably increased the number of the cells with typical senescence morphology. Four to 6 days after transfection with a mir-30d inhibitor, the percentage of β-galactosidase–positive cancer cells was significantly increased compared with controls. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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