Aging Overview

Aging gene

Gene name: SNHG6
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: SK-BR-3,MDA-MB-231
Gene ID: 641638
Category: ncRNA
Phenotype: Breast cancer
Experimental category: L
PMID: 30826970
Experiment: Prevent
Description: We found that the percentage of senescent cells was significantly increased in SNHG6 silenced SKBR-3 cells compared to that in scrambled siRNA transfected cells .SNHG6 silencing causes G1 cell cycle arrest in breast cancer cells and downregulation of Cyclin D1 and PCNA, two important factors in cell cycle progression, determined by RTqPCR following SNHG6 silencing.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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