Aging Overview

Aging gene

Gene name: MIR101-1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: MCF-7
Gene ID: 406893
Category: ncRNA
Phenotype: Aging
Experimental category: HL
PMID: 25353636
Experiment: SA-β-gal activity assay
Description: Further, continuous (upto 72 hrs) over-expression of miR-101 depicted an enhanced induction of senescence(2.3-Fold±0.25). miR-101 inhibition with anti-miR-101 oligonu-cleotides depicted a profile (0.9-Fold 60.25) which matched with the control cells.


Regulatory relationship

Target gene: UBE2N//SMARCA4
Official symbol(s): UBE2N//SMARCA4
R-AG-Target gene: Downregulation//Downregulation
Subcategory: Unclear
Target gene experiment: qRT-PCR
Target gene description: The validation of the two targets, UBE2N and SMARCA4, was established by measuring their endogenous cellular expression as well, which decreased significantly in over-expressing miR-101 cells.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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