Gene name: | MIR181A1 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | CD4+T |
Experiment: | SA-β-gal activity assay//EdU assay |
Description: | MiR-181a reconstitution significantly reduced the telomere length, increased SA-β-gal+ T cell frequency, and decreased EdU incorporation, in CD4+ T cells from patients with HCV. |
Target gene: | SIRT1 |
Official symbol(s): | SIRT1 |
R-AG-Target gene: | Downregulation |
Subcategory: | Unclear |
Target gene experiment: | Flow cytometry |
Target gene description: | Transfection of miR-181a precursor, but not the negative control, led to a significant down-regulation of Sirt1 expression in CD4+ T cells. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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