Aging Overview

Aging gene

Gene name: MIR145
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: T24
Gene ID: 406937
Category: ncRNA
Phenotype: Urothelial carcinoma
Experimental category: L
PMID: 26514209
Experiment: TUNEL assay//SA-β-gal activity assay
Description: miR-145 overexpression significantly suppressed cell proliferation. We found senescence to be induced in overexpressing T24 cells, although the number of apoptotic cells was not significantly increased .


Regulatory relationship

Target gene: SYNDECAN-1
Official symbol(s): SYNDECAN-1
R-AG-Target gene: Downregulation
Subcategory: Unclear
Target gene experiment: qRT-PCR
Target gene description: Overexpression of miR-145 significantly suppressed syndecan-1 mRNA.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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