Aging Overview

Aging gene

Gene name: MIR24-1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HDF
Gene ID: 407012
Category: ncRNA
Phenotype: Aging
Experimental category: L
PMID: 26748253
Experiment: SA-β-gal activity assay
Description: Notably a significantly higher percentage of senescent cells was observed in mir-24 transfected cells.


Regulatory relationship

Target gene: TOP1
Official symbol(s): TOP1
R-AG-Target gene: Downregulation
Subcategory: Unclear
Target gene experiment: Western blot
Target gene description: This initial finding could be experimentally corroborated by showing that mir-24 overexpression results in TOP1 protein downregulation.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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