Aging Overview

Aging gene

Gene name: PDCD10
Aging type: Accelerate
Aging characteristic: Others
Tissue type: --
Cell name: IMR-90
Gene ID: 11235
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 25655101
Experiment: Knockdown//SA-β-gal activity assay//qRT-PCR//BrdU assay
Description: When CCM3 was inhibited in these cells,4-OHT could still increase the number of γH2AX-positive cells,showing that H-ras was Activate in both control and CCM3-deficient cells. However, it did not inhibit DNA synthesis, nor did it induce a senescent morphology or senescence-associated β-galactosidase activity.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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