| Gene name: | YPEL3 |
| Aging type: | Accelerate |
| Aging characteristic: | Others |
| Tissue type: | Mammary Gland |
| Cell name: | MCF-7 |
| Gene ID: | 83719 |
| Category: | protein coding |
| Phenotype: | Breast cancer |
| Experimental category: | L |
| PMID: | 21671470 |
| Experiment: | MTT assay//Knockdown//SA-β-gal activity assay |
| Description: | When compared to MCF-7 cells, shYPEL3-expressing MCF-7 cells showed a statistically significant increase in cell numbers when grown over 10 days. Using an MTT-based assay, YPEL3 knockdown for six days led to an increase in cell numbers while YPEL3 induction over the same period resulted in a decrease in cell number.MCF7 cells stably selected for the loss of YPEL3 grown in charcoalstripped serum did not demonstrate an elevation in cellular senescence. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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