Gene name: | SNAIL |
Aging type: | Prevent |
Aging characteristic: | Others |
Tissue type: | -- |
Cell name: | LNCaP,PC-3 |
Gene ID: | 778762 |
Category: | protein coding |
Phenotype: | Prostate cancer |
Experimental category: | L |
PMID: | 20397042 |
Experiment: | Knockdown//SA-β-gal activity assay//Cell activity assay |
Description: | There was a significant 30–79% reduction in the relative ATP amount of SNAI1-siRNA-treated cells compared to cells treated with IR-siRNA after long-term knockdown of Snail for 5 days. In IRsiRNA-treated LNCaP cells, less than 5% stained positive for SA-β-gal, as compared to up to 30% of SNAI1-siRNA-treated LNCaP cells in some wells (p< 0.05). As expected from the morphology, only a few PC-3 cells were positive for SA-β-gal,independent of siRNA treatment (data not shown). |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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