Aging Overview

Aging gene

Gene name: SNAIL
Aging type: Prevent
Aging characteristic: Others
Tissue type: --
Cell name: LNCaP,PC-3
Gene ID: 778762
Category: protein coding
Phenotype: Prostate cancer
Experimental category: L
PMID: 20397042
Experiment: Knockdown//SA-β-gal activity assay//Cell activity assay
Description: There was a significant 30–79% reduction in the relative ATP amount of SNAI1-siRNA-treated cells compared to cells treated with IR-siRNA after long-term knockdown of Snail for 5 days. In IRsiRNA-treated LNCaP cells, less than 5% stained positive for SA-β-gal, as compared to up to 30% of SNAI1-siRNA-treated LNCaP cells in some wells (p< 0.05). As expected from the morphology, only a few PC-3 cells were positive for SA-β-gal,independent of siRNA treatment (data not shown).


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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