Gene name: | ENDOG |
Aging type: | Prevent |
Aging characteristic: | Others |
Tissue type: | Umbilical vein |
Cell name: | HUVEC |
Experiment: | Knockdown//SA-β-gal activity assay |
Description: | We found that knocking down EndoG in both early passage and late passage cells led to a significant delay in cell proliferation.This was accompanied by an increase in the percentage of cells staining positive for senescence-associated ?-galactosidase, suggesting that depletion of EndoG from human endothelial cells induces premature senescence. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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