Aging Overview

Aging gene

Gene name: ENDOG
Aging type: Prevent
Aging characteristic: Others
Tissue type: Umbilical vein
Cell name: HUVEC
Gene ID: 2021
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 20211237
Experiment: Knockdown//SA-β-gal activity assay
Description: We found that knocking down EndoG in both early passage and late passage cells led to a significant delay in cell proliferation.This was accompanied by an increase in the percentage of cells staining positive for senescence-associated ?-galactosidase, suggesting that depletion of EndoG from human endothelial cells induces premature senescence.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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