| Gene name: | MECP2 |
| Aging type: | Prevent |
| Aging characteristic: | Others |
| Tissue type: | Bone |
| Cell name: | mononuclear cell |
| Experiment: | Knockdown//Flow cytometry//SA-β-gal activity assay//Cell proliferation assay |
| Description: | We observed a significant reduction of S-phase cells, along with an increase of G1 cells in samples with partially silenced MECP2.The decrement of S-phase cells resulted in a decrease of cell proliferation as evaluated by cell count.We observed signs of senescence in cells treated with Ad-siRNA-MECP2, as detected by acid β-galactosidase, when compared with cells transduced with Ad-siRNACTRL. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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