Aging Overview

Aging gene

Gene name: RPS6KA6
Aging type: Accelerate
Aging characteristic: Others
Tissue type: Colon
Cell name: HCT116,IMR-90
Gene ID: 27330
Category: protein coding
Phenotype: Colorectal cancer
Experimental category: L
PMID: 19584160
Experiment: SA-β-gal activity assay//Western blot//qRT-PCR
Description: We tested RSK4 expression levels in IMR90 after inducing senescence by cumulative passages. Cells stopped proliferating, acquired the enlarged, flattened morphology typical of senescent cells, and were positive for SA-β-gal staining (data not shown). The senescent cells showed increased RSK4 expression on quantitative real-time PCR and Western blot .


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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