Aging Overview

Aging gene

Gene name: SUPT5H
Aging type: Prevent
Aging characteristic: Others
Tissue type: --
Cell name: HeLa
Gene ID: 6829
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 19210550
Experiment: Flow cytometry
Description: Tetracycline addition resulted in a gradual decrease in the populations corresponding to S and G2/M phases and a concomitant increase in the population corresponding to G1 phase.


Regulatory relationship

Regulatory pathway: P53
R-AG-Pathway: --
Official symbol(s): TP53
Pathway experiment: Knockdown//Western blot
Pathway description: We found that Spt5 depletion resulted in a significant elevation of the p53 protein level and a concomitant increase in the CDNK1A/p21 protein level.


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



Pathway view

About risk SNP and eQTL

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