Gene name: | MAP2K2 |
Aging type: | Accelerate |
Aging characteristic: | Others |
Tissue type: | -- |
Cell name: | IMR-90 |
Experiment: | Western blot//SA-β-gal activity assay |
Description: | MEK induced p53 (about three-fold induction), p21 (aboutfive-fold induction), and p16 (about six-fold induction).Finally, MEK1Q56P-expressing cells exhibited high levels of SA-β-gal activity, with a percentage of positive cells similar to that observed in Ras-expressing or late passage IMR90 cells. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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