Aging Overview

Aging gene

Gene name: MAP2K2
Aging type: Accelerate
Aging characteristic: Others
Tissue type: --
Cell name: IMR-90
Gene ID: 5605
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 9765203
Experiment: Western blot//SA-β-gal activity assay
Description: MEK induced p53 (about three-fold induction), p21 (aboutfive-fold induction), and p16 (about six-fold induction).Finally, MEK1Q56P-expressing cells exhibited high levels of SA-β-gal activity, with a percentage of positive cells similar to that observed in Ras-expressing or late passage IMR90 cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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