| Gene name: | PEX19 |
| Aging type: | Accelerate |
| Aging characteristic: | Others |
| Tissue type: | Human tumor tissue and normal tissue |
| Cell name: | U2OS,Human immortalized postcrisis cell,Fibroblast |
| Experiment: | Cell counting |
| Description: | Examination of 5AZA-dC response in Pex19p-overexpressing cells in comparison to the vector-transfected control cells revealed that the overexpression of Pex19p made the cells more sensitive to 5AZA-dC-induced senescence.Consistent with their stronger growth arrest. |
| Regulatory pathway: | P16 |
| R-AG-Pathway: | Upregulation |
| Official symbol(s): | CDKN2A |
| Pathway experiment: | Western blot |
| Pathway description: | Pex19p-overexpressing cells showed an enhanced induction of p16INK4A expression in response to 5AZA-dC treatment. |
Annotation:
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