Aging Overview

Aging gene

Gene name: PRPF19
Aging type: Prevent
Aging characteristic: Others
Tissue type: --
Cell name: HUVEC,I38-neo-1 ,I38-SNEV-1
Gene ID: 27339
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 16388800
Experiment: SA-β-gal activity assay//Comet assay
Description: I38-neo-1 cells entered growth arrest after around 8 PDs post-infection, where the cells showed the typical morphology of senescent cells and stained positive for SA-β-Gal . In contrast, I38-SNEV-1 cells at the same PD were characterized by a young morphology with no positive SA-β-Gal staining and entered replicative senescence around PD18pI.These data indicate that a high SNEV level correlates with a decrease of accumulated DNA damage during in vitro cultivation.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...