Gene name: | SOD1 |
Aging type: | Prevent |
Aging characteristic: | Others |
Tissue type: | -- |
Cell name: | WI-38,WI38-SV40 |
Experiment: | Cell morphological analysis//SA-β-gal activity assay |
Description: | In contrast,the SOD1 RNAi-transfected cells no longer divided.In addition the SOD1 RNAi morphology was aberrant and cells had an increased cell area and flattened appearance .WI38 SOD1 RNAi cells exhibited significantly stronger activity of senescence-associated β-galactosidase than the control cells. |
Target gene: | P53 |
Official symbol(s): | P53 |
R-AG-Target gene: | -- |
Subcategory: | Unclear |
Target gene experiment: | Immunostaining |
Target gene description: | In contrast to control cells, SOD1 RNAi-transfected cells displayed the p53 protein in the nucleus and at elevated expression levels. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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