| Gene name: | CDKN2A |
| Aging type: | Accelerate |
| Aging characteristic: | Others |
| Tissue type: | -- |
| Cell name: | TIG-3 |
| Experiment: | SA-β-gal activity assay |
| Description: | The both number of cells and [3H]thymidine incorporation are signi cantly decreased in H-ant-p16wt treated cells. Similar results were obtained using synchronized TIG-3 cells.The cells were then xed and stained for SA-β-gal, described to be expressed by senescent cells [27]. The enlarged growth-arrested cells gave a positive staining reaction. |
| Target gene: | PRB |
| Official symbol(s): | PRB |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | pRB is phosphorylated following serum stimulation in cells treated.However, pRB phosphorylation was not observed in cells treated with the H-ant-p16wt protein. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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