Aging Overview

Aging gene

Gene name: IL1A
Aging type: Prevent
Aging characteristic: Others
Tissue type: --
Cell name: endothelial cell
Gene ID: 3552
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 2218499
Experiment: Cell counting//Cell morphological analysis
Description: The daily addition of the IL-lot antisense oligomer to populationsofhuman endothelial cells at 20 population doublings resulted in asignificant extension of cell proliferation .Removal of the IL-la antisense oligomer from a cell population after an extended number of population doublings resulted in a reduction in the proliferative capacity of the monolayer and the generation of the senescent cell phenotype.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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