Aging Overview

Aging gene

Gene name: TRPC7
Aging type: Accelerate
Aging characteristic:
Tissue type: Lung
Cell name: Keratinocyte
Gene ID: 57113
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 31755176
Experiment: SA-β-gal activity assay//Western blot//Knockdown
Description: We found that after UVB irradiation, the knockdown of TRPC7 in keratinocytes significantly decreased the percentage of senescent cells, as determined by SA-β-gal staining .Furthermore, the knockdown of TRPC7 inhibited UVB-induced p53 expression in keratinocytes.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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