Aging Overview

Aging gene

Gene name: SDHD
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: Sdh4
Gene ID: 6392
Category: protein coding
Phenotype: Paraganglioma
Experimental category: L
PMID: 25328978
Experiment: Flow cytometry//Immunochemical staining
Description: It was observed that the lifespan of the sdh4DΔ and sdh4DΔ shh4DΔ mutants was reduced compared with the wild-type yeast at day 7. Our results revealed that cellular ROS in the sdh4DΔ shh4DΔ strain was higher than in the sdh4DΔ strain.In our results, the sdh4DΔ shh4DΔ strain showed lower mtDNA integrity and higher mtDNA mutability .


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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