Aging Overview

Aging gene

Gene name: MLH1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: CD34+
Gene ID: 4292
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 22740444
Experiment: qRT-PCR//Immunocytochemistry
Description: A 10-fold decrease in the RQ of MLH1 expression relative to the normalized sample was identified in 2 of the 5 adult CD34+samples.The percentage of CD34+cells with positive staining for MLH1 declined as a function of donor age. Across the donors analyzed, the percentage of CFC with MLH1 expression declined significantly as a function of age.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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