| Gene name: | ETV1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HCT116 |
| Gene ID: | 2115 |
| Category: | protein coding |
| Phenotype: | Colorectal cancer |
| Experimental category: | HL |
| PMID: | 23284306 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | Significantly, RNAi-mediated knockdown of ETV1 or ATR also induced senescence. |
| Target gene: | P53 |
| Official symbol(s): | P53 |
| R-AG-Target gene: | -- |
| Subcategory: | Unclear |
| Target gene experiment: | SA-β-gal activity assay//Knockdown//Western blot//Flow cytometry |
| Target gene description: | However, following knockdown of ETV1 or ATR, the induction of senescence was much greater in p53? HCT116 cells compared to p53+ HCT116 cells ,consistent with the difference in TERT levels .Notably, a similar preferential increase in the percentage of p53? HCT116 cells in G2/M occurred following knockdown of ETV1 or ATR. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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