Gene name: | STAT3 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | Lung |
Cell name: | Fibroblast |
Gene ID: | 6774 |
Category: | protein coding |
Phenotype: | Idiopathic pulmonary fibrosis |
Experimental category: | L |
PMID: | 30608861 |
Experiment: | SA-β-gal activity assay//ELISA//Knockdown//Western blot |
Description: | We found that treatment with STA-21 supressed levels of p21, as measured by immunoblot confirmed by graphed densitometry, and reduced staining of p21 in the nuclei of H2O2-treated fibroblasts.Reduced IL-6 secretion suggests an attenuated secretory profile, and decreased SA-β-Gal content measured using a cytochemical assay. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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