Aging Overview

Aging gene

Gene name: STAT3
Aging type: Accelerate
Aging characteristic:
Tissue type: Lung
Cell name: Fibroblast
Gene ID: 6774
Category: protein coding
Phenotype: Idiopathic pulmonary fibrosis
Experimental category: L
PMID: 30608861
Experiment: SA-β-gal activity assay//ELISA//Knockdown//Western blot
Description: We found that treatment with STA-21 supressed levels of p21, as measured by immunoblot confirmed by graphed densitometry, and reduced staining of p21 in the nuclei of H2O2-treated fibroblasts.Reduced IL-6 secretion suggests an attenuated secretory profile, and decreased SA-β-Gal content measured using a cytochemical assay.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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