Aging Overview

Aging gene

Gene name: TP53
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: Hs68
Gene ID: 7157
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 20569234
Experiment: Cell counting//SA-β-gal activity assay//Flow cytometry
Description: As a consequence of sustained p53 inhibition, both BJ and Hs68 cells escaped senescence and grew an additional 10 MPDs compared with control cells expressing pSuper vector .Ectopic expression of p53RR led to the establishment of senescence as measured by the acidic β-galactosidase assay and by the accumulation of cells in the G1 phase of the cell cycle.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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