Gene name: | TP53 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | Hs68 |
Experiment: | Cell counting//SA-β-gal activity assay//Flow cytometry |
Description: | As a consequence of sustained p53 inhibition, both BJ and Hs68 cells escaped senescence and grew an additional 10 MPDs compared with control cells expressing pSuper vector .Ectopic expression of p53RR led to the establishment of senescence as measured by the acidic β-galactosidase assay and by the accumulation of cells in the G1 phase of the cell cycle. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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