Aging Overview

Aging gene

Gene name: TERT
Aging type: Prevent
Aging characteristic:
Tissue type: Skin
Cell name: Fibroblast
Gene ID: 7015
Category: protein coding
Phenotype: Dyskeratosis congenita
Experimental category: L
PMID: 17381549
Experiment: Northern blot//TRAP assay//qRT-PCR
Description: Northern analysis also verified that cells transduced with the TER/eGFP construct expressed a mature TER RNA of approximately 450 bases in length.Expression of TER and TERT together in AD DC fibroblasts brought the level of telomerase to approximately the same as what was observed in normal fibroblasts that expressed TERT alone.Telomere signal was clearly much greater in AD DC or normal cells that expressed TER and TERT together.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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