| Gene name: | KRAS |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | MEF |
| Gene ID: | 3845 |
| Category: | protein coding |
| Phenotype: | Lung cancer |
| Experimental category: | L |
| PMID: | 26028035 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | Senescence-associated β-galactosidase staining was twofold higher in B600E/K12D cells compared with cells expressing one oncogene.Knockdown of either Cdkn2a (encoding p16 and p19) or Cdkn2b (encoding p15) expression restored proliferation of B600E/K12D MEFs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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