Aging Overview

Aging gene

Gene name: BECN1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HT22
Gene ID: 8678
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 30807795
Experiment: SA-β-gal activity assay//Western blot
Description: SA-β-gal staining gradually increased in a time-dependent manner when HT22 cells were treated with glutamate or H2O2. Also, levels of some senescence markers including the cyclin-dependent kinase inhibitors p16INK4a, p21, p53 and p27Kip1 increased over time in HT22 cells treated with glutamate or H2O2.Also, treatment of ALLN calpain inhibitor caused a decrease of these senescence markers in 0.5 mM H2O2 -treated HT22 cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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