Aging Overview

Aging gene

Gene name: KDM2B
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: MDA-MB-231,T47D,MCF-7
Gene ID: 84678
Category: protein coding
Phenotype: Breast cancer
Experimental category: L
PMID: 24853546
Experiment: SA-β-gal activity assay//Knockdown//Flow cytometry
Description: Flow cytometry of EtBr-stained semiconfluent cell cultures growing under normal tissue culture conditions revealed that the knockdown of NDY1 induces a partial G1 arrest in all the cell lines,and suggested that NDY1 contributes to progression from G1 to S. stained for β-galactosidase (β-gal), revealed that the knockdown elicits a strong senescence phenotype, which, however, is limited to T47D cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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