| Gene name: | ZBTB7A |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | FS090,SW 13 53 |
| Gene ID: | 51341 |
| Category: | protein coding |
| Phenotype: | Chondrosarcoma |
| Experimental category: | HL |
| PMID: | 22847180 |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | When compared with wild-type and EGFP-siRNA control cells, LRF-siRNA-expressing cells exhibited a significant accumulation of cells in the G 1 phase, with a corresponding reduction of cells in the S and G 2 /M phases .the percentages of β-galactosidase-positive cells were markedly increased in LRF-depleted FS090 (~50%) and SW1353 (~80%) cells . |
| Target gene: | P53//P21 |
| Official symbol(s): | P53//P21 |
| R-AG-Target gene: | --//-- |
| Subcategory: | Unclear |
| Target gene experiment: | Western blot |
| Target gene description: | The western blot results demonstrated that p53 was markedly elevated in LRF-depleted FS090 and SW1353 cells.The expression of p21 was also markedly increased. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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