Gene name: | BTG1 |
Aging type: | Accelerate |
Aging characteristic: |
Tissue type: | -- |
Cell name: | HCT-15,HCT116 |
Gene ID: | 694 |
Category: | protein coding |
Phenotype: | Colorectal cancer |
Experimental category: | HL |
PMID: | 27447746 |
Experiment: | SA-β-gal activity assay//PI staining |
Description: | BTG1 overexpression caused G2 arrest in HCT-15 cells (p<0.05), while G1 arrest in HCT-116 cells (p<0.05) by PI staining.A lower mitochondrial membrane potential by JC-1 staining and a higher senescence by β-galactosidase staining were detectable in HCT-116 transfectants than the mock and control, while there was no significant alteration in HCT-15 transfectants. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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