Aging Overview

Aging gene

Gene name: BTG1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HCT-15,HCT116
Gene ID: 694
Category: protein coding
Phenotype: Colorectal cancer
Experimental category: HL
PMID: 27447746
Experiment: SA-β-gal activity assay//PI staining
Description: BTG1 overexpression caused G2 arrest in HCT-15 cells (p<0.05), while G1 arrest in HCT-116 cells (p<0.05) by PI staining.A lower mitochondrial membrane potential by JC-1 staining and a higher senescence by β-galactosidase staining were detectable in HCT-116 transfectants than the mock and control, while there was no significant alteration in HCT-15 transfectants.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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