| Gene name: | TP53 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | HSC-1 |
| Gene ID: | 7157 |
| Category: | protein coding |
| Phenotype: | Skin cancer |
| Experimental category: | L |
| PMID: | 19009304 |
| Experiment: | SA-β-gal activity assay |
| Description: | Clones in which PA treatment induced p53 protein expression showed a Xat and extended morphology such as is commonly observed in senescent cells.we examined whether p53-expressing clones execute senescence-like growth arrest by the expression of a senescence marker, SA-β-gal.A large number of the PAtreated Clone 4 cells stained positive for SA-β-gal at 7 days, while none of the cloned cells not treated with PA were stained blue. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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