Aging Overview

Aging gene

Gene name: SIRT1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: A549
Gene ID: 23411
Category: protein coding
Phenotype: Idiopathic pulmonary fibrosis
Experimental category: L
PMID: 27979858
Experiment: Western blot
Description: We found that Sirt1 overexpression partially rescued miR-34a-induced cellular senescence in A549 cells, as evidenced by reduced expression of PAI-1 and p21 in these cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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