Aging Overview

Aging gene

Gene name: PLA2R1
Aging type: Accelerate
Aging characteristic:
Tissue type: --
Cell name: HMEC
Gene ID: 22925
Category: protein coding
Phenotype: Breast cancer
Experimental category: L
PMID: 23994771
Experiment: SA-β-gal activity assay//Colony formation assay//Western blot
Description: HMECs ectopically expressing PLA2R1 preferentially underwent proliferation arrest as measured by a colony formation assay, a decrease in the phosphor Ser10 of histone 3 (H3-pSer10), and an increased staining in the senescence-associated-β-galactosidase assay.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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