Aging Overview

Aging gene

Gene name: NUDT5
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: IMR-90
Gene ID: 11164
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 23581889
Experiment: SA-β-gal activity assay//Western blot
Description: Suppressed NUDT5 expression induced significant rates of senescence within one population doubling, as determined by the senescence-associated β-galactosidase (SA-β-gal) activity.Additionally, an immunoblotting analysis showed that the apoptosis-related proteins p53, p21, and caspase-3 were activated in shNUDT5 cells .


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...