Aging Overview

Aging gene

Gene name: RUNX1T1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: AML
Gene ID: 862
Category: protein coding
Phenotype: Acute leukemia
Experimental category: L
PMID: 15298716
Experiment: SA-β-gal activity assay//Knockdown
Description: After two or more electroporations with RUNX1-CBFA2T1 siRNA, but not with control siRNA, a significant fraction of the Kasumi-1 cells stain positive for β-galactosidase. Cell counting revealed up to 50% of senescent cells, whereas mock or control siRNA treatment caused only a minor increase in senescent cells compared to untreated cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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