Gene name: | RUNX1T1 |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | -- |
Cell name: | AML |
Gene ID: | 862 |
Category: | protein coding |
Phenotype: | Acute leukemia |
Experimental category: | L |
PMID: | 15298716 |
Experiment: | SA-β-gal activity assay//Knockdown |
Description: | After two or more electroporations with RUNX1-CBFA2T1 siRNA, but not with control siRNA, a significant fraction of the Kasumi-1 cells stain positive for β-galactosidase. Cell counting revealed up to 50% of senescent cells, whereas mock or control siRNA treatment caused only a minor increase in senescent cells compared to untreated cells. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
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