| Gene name: | RUNX1 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | AML |
| Gene ID: | 861 |
| Category: | protein coding |
| Phenotype: | Acute leukemia |
| Experimental category: | L |
| PMID: | 15298716 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | After two or more electroporations with RUNX1-CBFA2T1 siRNA, but not with control siRNA, a significant fraction of the Kasumi-1 cells stain positive for β-galactosidase. Cell counting revealed up to 50% of senescent cells, whereas mock or control siRNA treatment caused only a minor increase in senescent cells compared to untreated cells. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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