Aging Overview

Aging gene

Gene name: PMAIP1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: H460
Gene ID: 5366
Category: protein coding
Phenotype: Lungcancer
Experimental category: L
PMID: 24853380
Experiment: Cell morphological analysis
Description: We further found that NOXAsilenced H460 cells displayed classical senescence morphology with an enlarged and flattened cellular shape when MLN4924-induced apoptosis was blocked; this indicated a conversion of the cell death phenotype from apoptosis to senescence in these cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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