| Gene name: | CYP24A1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | Kidney |
| Cell name: | Primary renal proximal tubule epithelial cell |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | CYP24A1 overexpression induced senescence (increased G1 arrest) in normal conditions and induced apoptosis (increased sub-G1 fraction) in high glucose conditions. We did in fact see increased cellular senescence in cells overexpressing CYP24A1 that exceeded cellular senescence induced by high glucose alone, as shown by increased numbers of blue-stained cells . |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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