Aging Overview

Aging gene

Gene name: DKC1
Aging type: Prevent
Aging characteristic:
Tissue type: Embryo
Cell name: MEF
Gene ID: 1736
Category: protein coding
Phenotype: X-linked dyskeratosis congenita
Experimental category: L
PMID: 21241452
Experiment: SA-β-gal activity assay//Flow cytometry//Lifespan assay
Description: In 3% oxygen, △15 cells grew more slowly and entered senescence earlier than WT cells.△15 cells accumulated more ROS than WT cells and the difference became very significant with more PDs, even when cell .There was a significantly higher number of foci in D15 cells, and the difference was greater in high oxygen.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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