Gene name: | DKC1 |
Aging type: | Prevent |
Aging characteristic: |
Tissue type: | Embryo |
Cell name: | MEF |
Gene ID: | 1736 |
Category: | protein coding |
Phenotype: | X-linked dyskeratosis congenita |
Experimental category: | L |
PMID: | 21241452 |
Experiment: | SA-β-gal activity assay//Flow cytometry//Lifespan assay |
Description: | In 3% oxygen, △15 cells grew more slowly and entered senescence earlier than WT cells.△15 cells accumulated more ROS than WT cells and the difference became very significant with more PDs, even when cell .There was a significantly higher number of foci in D15 cells, and the difference was greater in high oxygen. |
Regulatory pathway: | -- |
R-AG-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation:
Loading,please wait...