Aging Overview

Aging gene

Gene name: CALCA
Aging type: Prevent
Aging characteristic:
Tissue type: Blood
Cell name: EPC
Gene ID: 796
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 20832068
Experiment: SA-β-gal activity assay//Telomerase activity assay
Description: CGRPI lentivirus transduction significantly reduced SA-β-gal positive senescent cells and elevated the activity of telomerase in AngII-treated EPCs.


Regulatory relationship

Target gene: KLOTHO
Official symbol(s): KLOTHO
R-AG-Target gene: Upregulation
Subcategory: Unclear
Target gene experiment: Western blot//qRT-PCR
Target gene description: Interestingly, the levels of both Klotho mRNA and secreted Klotho protein were remarkably increased by CGRPI over-expression.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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