Aging Overview

Aging gene

Gene name: CUX1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: IMR-90
Gene ID: 1523
Category: protein coding
Phenotype: Cancer
Experimental category: HL
PMID: 24618719
Experiment: Western blot//SA-β-gal activity assay
Description: Co-expression of p200 CUX1 enabled RAS expressing cells to proliferate normally and prevented SA-βgal activity.


Regulatory relationship

Target gene: OGG1
Official symbol(s): OGG1
R-AG-Target gene: Activation
Subcategory: Unclear
Target gene experiment: Western blot
Target gene description: The enzymatic activity of OGG1 was greatly stimulated by recombinant CUX1 proteins containing one or more Cut repeat domain(s): CR2CR3HD, CR3HD, and CR1CR2.

Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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