Aging Overview

Aging gene

Gene name: MAD2L1
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: MKN45
Gene ID: 4085
Category: protein coding
Phenotype: Gastric cancer
Experimental category: L
PMID: 25483095
Experiment: SA-β-gal activity assay//qRT-PCR
Description: With this experiment, we determined that the fraction of SA-β-gal-positive cells increases 3d after Mad2 depletion. When we analyzed its activation after 72 h of PTX treatment, we observed an increase in p53 mRNA levels in cells lacking Mad2.IL-6 (and not IL-8) expression was attenuated when Mad2 was decreased.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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