Aging Overview

Aging gene

Gene name: WRN
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: hTERT+ Fibroblast
Gene ID: 7486
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 12842909
Experiment: SA-β-gal activity assay//Knockdown
Description: WRN-depleted cells proliferated poorly compared to empty vector or cells expressing a control RNAi . MYC overexpression failed to rescue theproliferative capacity of WRN-depleted cells and led to a significant increase in the percentage of SA-β-gal-positive cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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