| Gene name: | ATF1 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | Sarcoma-iPSC MEF |
| Gene ID: | 466 |
| Category: | protein coding |
| Phenotype: | Clear cell sarcoma |
| Experimental category: | HL |
| PMID: | 31488818 |
| Experiment: | Cell morphological analysis//SA-β-gal activity assay//RT-PCR |
| Description: | EWS/ATF1-expressing sarcoma-iPSC MEFs ceased growth and changed morphology into a large and flat shape.The senescenceassociated β galactosidase (SA β-gal)-positive cell ratio was significantly higher in EWS/ATF1-expressing MEFs than in non-expressing MEFs,suggesting that EWS/ATF1 induces premature senescence in sarcoma-iPSC MEFs. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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