| Gene name: | SLC4A2 |
| Aging type: | Prevent |
| Aging characteristic: |
| Tissue type: | -- |
| Cell name: | BEC |
| Gene ID: | 6522 |
| Category: | protein coding |
| Phenotype: | Primary biliary cholangitis |
| Experimental category: | L |
| PMID: | 27592379 |
| Experiment: | SA-β-gal activity assay//Knockdown |
| Description: | Transfection of BEC with AE2-specific siRNA that reduced AE2 expression significantly increased the proportion of SA-β-gal-positive cells (p < 0.05) and this effect was significantly inhibited by NAC (p < 0.05), indicating that the increased cellular senescence is indeed caused by the reduced level of AE2 expression. |
| Regulatory pathway: | -- |
| R-AG-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation:
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