Aging Overview

Aging gene

Gene name: MANF
Aging type: Prevent
Aging characteristic:
Tissue type: Adipose
Cell name: --
Gene ID: 7873
Category: protein coding
Phenotype: Aging
Experimental category: HL
PMID: 31489403
Experiment: SA-β-gal activity assay//Knockdown//qRT-PCR
Description: We also found signs of cellular senescence in MANFHet mice, but not WT littermates, at 10 months of age: elevated senescence-associated βGal activity in subcutaneous and visceral WAT, increased levels of 4-HNE adducts, and increased expression of p16 and IL-6.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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