Aging Overview

Aging gene

Gene name: G6PD
Aging type: Prevent
Aging characteristic:
Tissue type: --
Cell name: HFF
Gene ID: 2539
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 10980404
Experiment: SA-β-gal activity assay//Cell morphological analysis
Description: There was an increase in the percentage of SA-β-Gal positive HFF1 cells, from less than 8% at PDL 22 to about 50% at PDL 52, and to over 95% at PDL 60. The majority of HFF3 cells remained SA-β-Gal negative at PDL 52, and a few cells (less than 5%) were stained positive at PDL 60.Some HFF1 cells showed the senescent morphology at PDL 22, and by PDL 60, nearly all the cells were senescen. By contrast, the HFF3 cells did not show such morphology even at passages up to PDL 60.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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