Aging Overview

Aging gene

Gene name: FANCD2
Aging type: Accelerate
Aging characteristic:
Tissue type: Foreskin
Cell name: Fibroblast
Gene ID: 2177
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 21995812
Experiment: Cell counting//BrdU assay//Knockdown
Description: Numbers of Chk1 siRNA- and FANCD2 siRNA-transfected cells decreased equally until day 3 after irradiation.Forty-eight hours after siRNA transfection, fibroblasts were incubated with BrdU for 24 h. Four percent of the control siRNA-treated fraction stained positive for the nucleotide analogue.Remarkably, only 9% of the FANCD2 siRNA- transfected fibroblasts were BrdU-positive.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

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