Aging Overview

Aging gene

Gene name: CHEK1
Aging type: Accelerate
Aging characteristic:
Tissue type: Foreskin
Cell name: Fibroblast
Gene ID: 1111
Category: protein coding
Phenotype: Aging
Experimental category: L
PMID: 21995812
Experiment: Cell counting//BrdU assay
Description: Numbers of Chk1 siRNA- and FANCD2 siRNA-transfected cells decreased equally until day 3 after irradiation.Forty-eight hours after siRNA transfection, fibroblasts were incubated with BrdU for 24 h. Four per cent of the control siRNA-treated fraction stained positive for the nucleotide analogue. Chk1 depletion induced BrdU incorporation in 15% of the cells.


Regulatory pathway: --
R-AG-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.



About risk SNP and eQTL

Loading,please wait...